Gathering Three | Overcoming Difficulties in mRNA Raw Material Technology and Quality Control
Release time:
2023-08-04 17:23
Gathering Three | Overcoming Difficulties in mRNA Raw Material Technology and Quality Control
The raw material process and quality control of mRNA vaccine are the key to the preparation of the vaccine. At present, we have gathered the experience and expertise of three biotechnology companies to overcome the difficulties in mRNA raw material technology and quality control.
First, we focus on the selection and purification of raw materials. High-quality mRNA vaccines must use high-purity nucleotides as raw materials. We use advanced purification techniques to extract nucleic acids from cells and screen mRNA with high purity through precise quality control. At the same time, we optimized the synthesis process of nucleotides to ensure their structural stability and consistency to improve the efficacy and safety of the vaccine.
Second, we address the difficult problem of mRNA modification. In mRNA vaccines, modified nucleotides can enhance the stability and translation efficiency of mRNA. We will combine the research results of the three companies to study the effect of different modification methods on the vaccine effect, and optimize the modification process to improve the expression level and immune effect of mRNA vaccine.
We pay attention to the strict implementation of quality control. Strictly control the quality of each production link, from raw material procurement to each step of the production process, to ensure the quality and consistency of mRNA vaccine preparation. We will use advanced analytical techniques and quality standards to ensure that the purity, concentration and activity of each batch of vaccine meet the requirements, so as to ensure its safety and effectiveness.
By pooling the professional experience and technical strength of the three companies, we will overcome the difficulties in the mRNA raw material process and quality control, and provide a strong guarantee for the preparation of safe mRNA vaccines.
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